The effect of botulinum toxin-A injection into the masseter muscles on prevention of plate fracture and post-operative relapse in patients receiving orthognathic surgery
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½Å¼±È£ ( Shin Sung-Ho ) - Gangneung-Wonju National University College of Dentistry Department of Oral and Maxillofacial Surgery
°¿¹Áø ( Kang Yei-Jin ) - Gangneung-Wonju National University College of Dentistry Department of Oral and Maxillofacial Surgery
±è¼º°ï ( Kim Seong-Gon ) - Gangneung-Wonju National University College of Dentistry Department of Oral and Maxillofacial Surgery
Abstract
Background: Botulinum toxin-A (BTX-A) injection into muscle reduces muscular power and may prevent post-operative complication after orthognathic surgery. The purpose of this study was (1) to evaluate BTX-A injection into the masseter muscle on the prevention of plate fracture and (2) to compare post-operative relapse between the BTX-A injection group and the no injection group.
Methods: Sixteen patients were included in this study. Eight patients received BTX-A injection bilaterally, and eight patients served as control. All patients received bilateral sagittal split ramus osteotomy for the mandibular setback and additional surgery, such as LeFort I osteotomy or genioplasty. Post-operative plate fracture was recorded. SNB angle, mandibular plane angle, and gonial angle were used for post-operative relapse.
Results: Total number of fractured plates in patients was 2 out of 16 plates in the BTX-A injection group and that was 8 out of 16 plates in the no treatment group (P?=?0.031). However, there were no significant differences in post-operative changes in SNB angle, mandibular plane angle, and gonial angle between groups (P?>?0.05).
Conclusions: BTX-A injection into the masseter muscle could reduce the incidence of plate fracture.
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Botulinum toxins; Type A; Fracture fixation; Internal; Osteotomy; Sagittal split ramus; Postoperative complications
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